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PGRN Ontology Network Resource (PHONT)

Our goals are to support meta-analyses, achieve translational goals, and facilitate the messaging of pharmacogenomics-related data from and potentially into clinical environments such as EMRs. Read more.

Announcements

  • We are analyzing data dictionaries from all PGRN sites and mapping the data elements with these data dictionaries to standardized data models and terminologies. We will be publishing the results of this analysis on our page shortly. Please email your questions to PHONT
  • Ongoing collaborats with PharmGKB are taking place to incorporate terms from RxNorm and NDF-RT into their data set.
  • We are collaborating with PG-POP to create standardized representations of phenotype algorithms to mine EMR data.

Resources

Clinical Element Models (CEMs)
  • Detailed clinical models are a standardized model that serve as the basis for retaining computable meaning when data is exchanged between heterogeneous computer systems. Detailed clinical models are also the basis for shared computable meaning when data is referenced in decision support logic.
  • PHONT is leveraging work on a Core set of CEMs created by a collaboration between Mayo Clinic and Intermountain Healthcare as part of the SHARPn group at Mayo Clinic.


Infrastructure
  • PHONT utilizes a wide variety of computational infrastructure to support data harmonization and standardization activities. This infrastructure includes terminology services that provide access to standard terminologies, as well as metadata repositories and harmonization platforms.
Terminologies
  • PHONT provides access to standard terminologies that meet U.S. Meaningful Use requirements. Value sets related to pharmacogenomics data sets will be defined using these terminologies.

Related Links

PG-POP
PharmGKB
PHONT profile on PGRN.org
PHONT Network Access Resource Guide
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